Chancroid infection

Chancroid - 2015 STD Treatment Guidelines

Granuloma Inguinale (Donovanosis) - 2015 STD Treatment Guidelines

There are many kinds of sexually transmitted diseases and infections. And they are very common - more than half of all of us will get one at some time in our lives. Use the list above to find out about each kind of STD.

Donovanosis or “granuloma inguinale” is a bacterial infection of the genital region. It is chronic and progressive.

Granuloma inguinale, contagious sexually transmitted disease occurring predominantly in tropical areas and characterized by deep purulent ulcers on or near the genital organs. Encapsulated bacilli called Donovan bodies (Calymmatobacterium granulomatis) occur in smears from the lesions or in biopsy

DefinitionDonovanosis (granuloma inguinale) is a sexually transmitted disease that is rarely seen in the United States.

Donovanosis, a chronic cause of genital ulceration, has recently been the subject of renewed interest after a long period of relative obscurity.

Australian STI Management Guidelines for Use in Primary Care are nationally endorsed guidelines on the testing, diagnosis, management and treatment of STIs.

Donovanosis (granuloma inguinale) is a sexually transmitted disease that is rarely seen in the United States.

DefinitionChancroid is a bacterial infection that is spread through sexual contact.

Chancroid is a bacterial infection that is spread through sexual contact.

Herpes simplex virus infection and syphilis are the most common causes of genital ulcers in the United States. Other infectious causes include chancroid, lymphogranuloma venereum, granuloma inguinale (donovanosis), secondary bacterial infections, and fungi. Noninfectious etiologies, including sexual trauma, psoriasis, Behçet syndrome, and fixed drug eruptions, can also lead to genital ulcers. Although initial treatment of genital ulcers is generally based on clinical presentation, the following tests should be considered in all patients: serologic tests for syphilis and darkfield microscopy or direct fluorescent antibody testing for Treponema pallidum, culture or polymerase chain reaction test for herpes simplex virus, and culture for Haemophilus ducreyi in settings with a high prevalence of chancroid. No pathogen is identified in up to 25 percent of patients with genital ulcers. The first episode of herpes simplex virus infection is usually treated with seven to 10 days of oral acyclovir (five days for recurrent episodes). Famciclovir and valacyclovir are alternative therapies. One dose of intramuscular penicillin G benzathine is recommended to treat genital ulcers caused by primary syphilis. Treatment options for chancroid include a single dose of intramuscular ceftriaxone or oral azithromycin, ciprofloxacin, or erythromycin. Lymphogranuloma venereum and donovanosis are treated with 21 days of oral doxycycline. Treatment of noninfectious causes of genital ulcers varies by etiology, and ranges from topical wound care for ulcers caused by sexual trauma to consideration of subcutaneous pegylated interferon alfa-2a for ulcers caused by Behçet syndrome.