Degenerative nerve diseases affect many of your body's activities, such as balance, movement, talking, breathing, and heart function. Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is unknown.Degenerative nerve diseases include Alzheimer's disease Amyotrophic lateral sclerosisFriedreich's ataxia Huntington's disease Lewy body diseaseParkinson's disease Spinal muscular atrophyDegenerative nerve diseases can be serious or life-threatening. It depends on the type. Most of them have no cure. Treatments may help improve symptoms, relieve pain, and increase mobility.