| Down syndrome | |
|---|---|
| Other names | Down's syndrome, Down's, trisomy 21 |
 |
|
| An eight-year-old boy from British Columbia displaying characteristic facial features of Down syndrome | |
| Specialty | Medical genetics, pediatrics |
| Symptoms | Delayed development, characteristic physical features, mild to moderate intellectual disability[1] |
| Usual onset | Mostly at conception, rarely after fertilization[2] |
| Duration | Lifelong |
| Causes | Third copy of chromosome 21[3] |
| Risk factors | Older age of mother, prior affected child[4][5] |
| Diagnostic method | Prenatal screening, genetic testing[6] |
| Treatment | Physical therapy, Occupational therapy, Speech therapy, Educational support, Supported work environment[7][8] |
| Prognosis | Life expectancy 50 to 60 years (developed world)[9][10] |
| Frequency | 5.4 million (0.1%)[1][11] |
| Named after | John Langdon Down |
| Down syndrome | |
|---|---|
| Other names | Down's syndrome, Down's, trisomy 21 |
|
|
| An eight-year-old boy from British Columbia displaying characteristic facial features of Down syndrome | |
| Specialty | Medical genetics, pediatrics |
| Symptoms | Delayed development, characteristic physical features, mild to moderate intellectual disability[1] |
| Usual onset | Mostly at conception, rarely after fertilization[2] |
| Duration | Lifelong |
| Causes | Third copy of chromosome 21[3] |
| Risk factors | Older age of mother, prior affected child[4][5] |
| Diagnostic method | Prenatal screening, genetic testing[6] |
| Treatment | Physical therapy, Occupational therapy, Speech therapy, Educational support, Supported work environment[7][8] |
| Prognosis | Life expectancy 50 to 60 years (developed world)[9][10] |
| Frequency | 5.4 million (0.1%)[1][11] |
| Named after | John Langdon Down |
